IMWITOR 491

$0.00

Glyceryl Monostearate

Product Application: Tablet
Product Certification: Non-GMP
Pharmaceutical Category: Binder,Emulsifier,Partial glycerides
Supplier: IOI Oleochemical
Download Product Spec Sheet

IMWITOR 491 is an ester from the plant fatty acids stearic and palmitic acid with plant derived glycerol. The monoester content is more than 90%. It is manufactured from hydrogenated rape seed oil and glycerol. This ester is a white to slightly yellow, wax-similar powder with a neutral and slightly fatty odour and taste. It is a lipophilic matrix suitable for oral solid dosage forms (granulation, hot melt technique), used as tablet lubricant, O/W co-emulsifier, emulsion stabilizer, stiffening and dispersing agent for pigments.

Melting Point [C°] 66-77
HLB Value ~4
Monoglycerides [%] >90.0%

IMWITOR 491 is insoluble in water, soluble in fatty oils, mineral oil, diethyl ether, acetone and hot ethyl alcohol. It does not contain antioxidants, stabilizers, solvents or other additives.

IMWITOR 491 Applications

IMWITOR 491 is often used in formulations of pharmaceuticals. Due to its surface activity (HLB value approx. 4) it shows the following functions: non-ionic emulsifier, co-emulsifier, stabilizer, dispersing agent, solubilizer, lubricant, softener, consistency regulator, binding agent and retarding agent. Typical dosage: 1-3 %.

IMWITOR 491 is part of the IMWITOR line of products that are Partial glycerides. Partial glycerides are esters of glycerol with fatty acids, whereby only part of the existing hydroxyl groups is esterified. Some hydroxyl groups within the glycerol ester are free, contributing to the hydrophilic properties of the material. Short-chain partial glycerides are more hydrophilic and have excellent solvent properties for many poorly soluble drugs.

Azelis Canada is a supplier of IMWITOR and all other Pharmaceutical lines from IOI Oleochemical. Speak with your Azelis Canada representative to find the best option for your formulation!

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