Glycerol Monocaprylocaprate, Type IProduct Application: Defoamer,Penetration Enhancer
Product Certification: GMP,Halal,OU Kosher
Pharmaceutical Category: Partial glycerides
IMWITOR 742 is a blend of mono-, di- and triglycerides, mainly of caprylic (C8H16O2) and capric acid (C10H20O2). Glycerol and fatty acids are derived from vegetable sources.
Melting Point [C°] ~25
Monoglycerides [%] ~53%
The colour of IMWITOR 742 is white to yellowish and it is typical for the product that it might occur in different shapes, ranging from a crystalline solid or partly solid to liquid or paste, depending on the monoester content and on the ambient temperatures. Due to this and in order to obtain a homogeneous product it is recommended to melt the complete container at approx. 60°C for at least 12 hours. It is advisable to check from time to time whether the product is already molten or not. Although it is recommended not to heat over 25°C for a longer time, this shortly applied heating procedure does not affect the quality or the applicational properties. IMWITOR 742 exhibits a slight odour of coconut and a fatty, scratchy and bitter taste and it melts at about 25°C forming an oily, yellowish liquid. IMWITOR 742 contains no unsaturated components and is thus stable against oxidation even at elevated temperatures (f.i. 60°C, 14d)
IMWITOR 742 Applications
IMWITOR 742 is used in oral, topical, rectal, vaginal und nasal preparations in the amount of 3 – 15 %, depending on the kind and quantity of the active ingredients used. It acts as a solubilizer for poorly soluble drugs in oral administration forms (i.e. capsules). IMWITOR® 742 also functions as a penetration enhancer in topical drug forms. IMWITOR 742 is surface-active and acts as a plasticizer in tablet coatings, as co-emulsifier in emulsions and as defoaming agent.
Azelis Canada is a supplier of IMWITOR and all other Pharmaceutical lines from IOI Oleochemical. Speak with your Azelis Canada representative to find the best option for your formulation!