Microcrystalline Cellulose (NF, Ph. Eur.,JP), E460
Glyceryl Monostearate (NF, JP), E471
Product Certification: Gluten-free
Pharmaceutical Category: Direct compression,Self Lubricating Excipient
LubriTose MCC is a co-processed excipient consisting of NF/Ph. Eur./JP compliant Microcrystalline Cellulose (MCC) and NF/JP compliant Glyceryl Monostearate. It is meant to be used in standard direct tabletting applications. It is only necessary to add the API (active pharmaceutical ingredient), any other desired ingredient, and proceed to tabletting. The Glyceryl Monostearate is co-processed in to act as a lubricant and therefore it is not necessary to add a lubricant such as Magnesium Stearate to the tabletting formulation. By using LubriTose™, you get a true direct tabletting operation as the lubricant addition step is removed. LubriTose™ is ideal for continuous systems and also for QbD.
LubriTose MCC was specifically designed to eliminate processing issues , product rejections and tablet press speed limitations typically encountered when Magnesium Stearate is used as the lubricant.
LubriTose MCC Advantages
- Less processing steps
- Eliminates need for external lubricant and time sensitive blending
- Improve flow & tablet weight uniformity
- No impact on compression or API dissolution
LubriTose, by Kerry, is available as Anhydrous Lactose, Spray Dried Lactose, Microcrystalline Cellulose (MCC), or mannitol as a ‘base’ excipient.
LubriTose™ has less rounder, smoother particles and less fines due to the agglomeration which equates to less dusting and better flow.