Sheffield Monohydrate 80M
Lactose MonohydrateProduct Application: Capsule,Powder Blend,Tablet
Product Certification: Gluten-free,Kosher,Rennet free
Pharmaceutical Category: Bulking agent,Crystalline Monohydrate,Diluent,Filler
Sheffield Monohydrate 80M is recommended as an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders, and other preparations. It also has applications as a nutrient and multifunctional ingredient in infant formulas, geriatric, dietetic and health foods and may be used as an ingredient in culture media.
Monohydrate Lactose is a disaccharide obtained from the whey fraction of milk, and consists of one glucose and one galactose moiety. Sheffield™ Monohydrate 80M Lactose is crystalline alpha-monohydrate anomers. Sheffield™ brand meets all requirements of the National Formulary as well as the European and Japanese Pharmacopeias.
Particle Size Curves
Sheffield Monohydrate 80M Advantages
- Inert material, high purity, low colour
- Moisture stable – 4 year shelf life
- Physically and chemically stable
- High degree of crystallinity, low amorphous content
|Product||Angle of Repose (α)||Compressibility (Carr’s Index)||Flowability (g/sec)|
|Sheffield Monohydrate 80M||54.9||33.6||0.91|
|Sheffield Monohydrate 312||54.9||33.6||0.91|
Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending. The mixture is then dried and sized, and compressed into tablets. During dry granulation, the particle size is enhanced by aggregating the particles by roller compaction and then milling to the desired size.